| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0ffd5528fd07384d7b07ab484ed5b143 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2121-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-506
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-513
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-496 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-513
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-506
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-38 |
| filingDate |
2010-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_666872b84e85beacffca50ee4a7ae4d3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c55d0ef58aec0d18e1c5d016025bf31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9131374855ec78d53b111deaa0dab41
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86146b0bc371459f4a2e9f0e0e79b87b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c737d9b660f98de9e2083f07ce911e11 |
| publicationDate |
2018-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-108752280-A |
| titleOfInvention |
Heat shock protein binding compounds, compositions, and methods of making and using same |
| abstract |
The present invention relates to heat shock protein binding compounds, compositions and methods of making and using the same. The present invention relates to a compound represented by general formula (I) or (I') or a pharmaceutically acceptable salt thereof; a pharmaceutical composition containing at least one of said compounds; a method for preparing at least one of said compounds; using Methods of treating and/or preventing various cancers and/or proliferative disorders with at least one of said compounds; methods of monitoring the effectiveness of anticancer therapies against various cancers using at least one of said compounds. In one embodiment, the invention relates to compounds that bind to heat shock protein 70 Hsp70 with a certain level of specificity. In another embodiment, the present invention relates to compounds that bind with a certain level of specificity to inhibit heat shock protein 70 Hsp70 and heat shock homologous protein 70 Hsc70. |
| priorityDate |
2009-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |