http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108752246-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d7562a03fba8427deffd7e352c618b49 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C315-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C315-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C317-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C315-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C315-04 |
| filingDate | 2018-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78faaa4ef00f012418dae495faf0a531 |
| publicationDate | 2018-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108752246-A |
| titleOfInvention | A kind of industrialization production method of efficient 2- nitryl-4-thiamphenicol benzoic acids |
| abstract | The present invention relates to technical field of organic synthesis, specially a kind of industrialization production method of efficient 2- nitryl-4-thiamphenicol benzoic acids, it can preferably improve reacts phenomenon difficult and that products collection efficiency is relatively low caused by molecular oxidation current potential is higher in 2- nitro -4- methylsulfonyltoluene oxidation process.Its preparation process includes mainly：After 2- nitro -4- methylsulfonyltoluenes are mixed with iron powder, bromine is added thereto, is uniformly mixed, Sodamide is added thereto later, it is made fully to react, final product liquid is used for subsequent reactions material；Product liquid is mixed with sulfuric acid, nitric acid, stirs, oxidation reaction is carried out under catalysts conditions；Water is added into the mixed liquor of above-mentioned preparation, reaction is hydrolyzed；Water is added into material obtained above, filtering, centrifugation respectively obtain crude product and mother liquor；Calcium nitrite and hydrochloric acid are added into crude product obtained above, stirring, the reaction was complete；Sodium hypophosphite is added thereto, stirs, the reaction was complete, obtains product. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111254456-A |
| priorityDate | 2018-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 53.