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filingDate 2018-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108744060-B
titleOfInvention Bone repair material capable of being injected with multiple pore structures and preparation method thereof
abstract The invention provides a bone repair material capable of being injected with multiple pore structures and a preparation method thereof, the bone repair material comprises powder, a curing liquid A and a curing liquid B, the powder is hydroxyapatite composite polylactic acid-glycolic acid copolymer porous microspheres, the curing liquid A is a collagen solution, the curing liquid B is a dopamine-hyaluronic acid aqueous solution, the powder is dispersed in the curing liquid A and then uniformly mixed with the curing liquid B, the pH value is adjusted to 7.5-8.5, phenolic hydroxyl groups of dopamine-hyaluronic acid can be oxidized and crosslinked to form dopamine-hyaluronic acid copolymer hydrogel, and the hydroxyapatite composite polylactic acid-glycolic acid copolymer porous microspheres and the collagen are distributed in a three-dimensional network structure of the dopamine-hyaluronic acid copolymer hydrogel. The bone repair material has a multi-hole structure suitable for cell growth, can increase the tightness of combination between the bone repair material and autologous bones, and is expected to be applied to the fields of tissue repair such as skin filling and the like and cosmetology by adjusting the composition ratio.
priorityDate 2018-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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