| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_892c33e4735b1781cb423ea035722efc |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P39-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-08 |
| filingDate |
2018-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f7061c6bc5e304e40693d6c1bd5c6d3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c3f32083c00d87b9be01b177afe97c7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad9c7a3e710c7d753e25c0a1d5dfad7f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7a0c7844adff823088f6a2d019384f2 |
| publicationDate |
2018-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-108743920-A |
| titleOfInvention |
Applications of the YAP in preparing treatment and/or preventing animal osteoarthritis product |
| abstract |
The invention discloses applications of the YAP in preparing treatment and/or preventing animal osteoarthritis product.It is a discovery of the invention that YAP has following function：Treatment and/or prevention animal osteoarthritis；Treatment and/or the osteoarthritis for preventing the induction of animal anterior cruciate ligament-transection；Delay the aging of mescenchymal stem cell；Delay the replicative senescence of mescenchymal stem cell；Delay the pathological seaility of mescenchymal stem cell.The experiment proves that YAP has the function of explicitly delaying mescenchymal stem cell aging, and YAP has specific therapeutic effect in osteoarthritis disorders.The present invention provides new thinking to develop for the gene therapy of osteoarthritis, and expands the selectable range of clinical gene therapy. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020024773-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111744002-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111744002-B |
| priorityDate |
2018-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |