| abstract |
The invention discloses a kind of Pseudobulbus Bletillae (Rhizoma Bletillae) extract and its application, the Pseudobulbus Bletillae (Rhizoma Bletillae) extract is prepared as follows：Bletilla dry powder is taken, with volumetric concentration 60-90% ethanol water refluxing extractions, filtrate, as bletilla alcohol extract are collected in filtering；Bletilla alcohol extract is adsorbed through polyamide, D101 macroporous resin columns successively, 35%~45% ethanol eluate of collected volume concentration, and evaporated under reduced pressure obtains Pseudobulbus Bletillae (Rhizoma Bletillae) extract.The present invention confirms the bletilla active component EFB of the present invention by the experiment of internal SD rat model of chronic bronchitis, it can be by inhibiting the inflammatory factors such as TNF-α, IL-1 β, IL-6, with by improving oxidative stress, therapeutic effect is played to chronic bronchitis. |