http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108743582-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9ca08d1a50489e426d12475ac97f8e47 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-365 |
filingDate | 2018-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8c79100f61e41cde65ddc7042e75010 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ce6550914c4bd529a983c2e8cec2c4d |
publicationDate | 2018-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108743582-A |
titleOfInvention | A kind of TLR5 activator enhances the purposes of tumor cell vaccine immunogenicity for activation antigen presenting cells in turn |
abstract | The invention discloses a kind of TLR5 activator for activation antigen presenting cells and then enhances the purposes of tumor cell vaccine immunogenicity.Present invention discover that, 12, cis- manaca tower pavilion first, manaca tower pavilion first, the manaca tower pavilion fourths of 15-, bubble manaca are pungent, cherimoya essence, remove acetyl Uvaria microcarpa element, acetyl isouvaretin and Mo Chuilin is gone to significantly improve the content of antigen presenting cell surface marker by increasing the expression of TLR5 in antigen presenting cell (Dendritic Cells DC), have the function of activation antigen presenting cells;One skilled in the art will appreciate that activation antigen presenting cells can enhance the immunogenicity of tumor cell vaccine, the immune effect of tumor cell vaccine is improved, therefore above compound may be used as the immunologic adjuvant of tumor cell vaccine. |
priorityDate | 2018-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 208.