http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108743527-B

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filingDate 2018-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2020-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108743527-B
titleOfInvention Tirofiban hydrochloride injection and preparation method thereof
abstract The invention relates to a tirofiban hydrochloride-containing injection, belonging to the field of pharmaceutical preparations. The injection contains tirofiban hydrochloride, sodium alginate, a pH regulator and water, and is prepared by the steps of dissolving citric acid and sodium citrate in 10-50% of water to prepare a citric acid-sodium citrate buffer solution, dissolving the tirofiban hydrochloride and the sodium alginate in the water, and mixing the two solutions; adjusting pH, filtering, packaging, sterilizing, inspecting, and packaging. The invention selects the osmotic pressure regulator preferably, has high active substance content, can keep the stability of the main drug under the conditions of high temperature, illumination and the like, has simple preparation process, is suitable for industrial production and is convenient for market popularization.
priorityDate 2018-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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