http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108728490-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-14043 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-16034 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-16022 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-105 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-245 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62 |
| filingDate | 2018-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108728490-B |
| titleOfInvention | Baculovirus vector-based carp herpesvirus II type DNA vaccine and construction method and application thereof |
| abstract | The invention relates to a baculovirus vector-based cyprinid herpesvirus II type DNA vaccine and a construction method and application thereof. Optimizing codons of 1-186, 993-1197, 603-783 and 85-186 nt region sequences of cyprinid herpesvirus II type ORF72, ORF66, ORF81 and ORF82, chemically synthesizing ORF72-ORF66-ORF81-ORF82 fusion sequence, and cloning into baculovirus transfer vector pFSATBac under the control of promoter TM Dual construction recombinant plasmid pFSATBac TM The plasmid is converted into DH10/Bac competent cells to obtain Bacmid-FA-D4ORF, and Bacmid-FA-D4ORF DNA is transfected into cultivated silkworm cells to obtain BmNPV-FA-D4ORF, namely the rhabdovirus II type DNA vaccine based on the baculovirus vector. The DNA vaccine can be used for immunizing carassius auratus gibelio by injection or oral administration or soaking, and reducing gill hemorrhage of carassius auratus gibelio. |
| priorityDate | 2018-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.