http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108728473-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2002-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-746 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-195 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-46 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-02 |
filingDate | 2017-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108728473-B |
titleOfInvention | Recombinant vector and recombinant strain for expressing helicobacter pylori NapA protein, and preparation method and application thereof |
abstract | The invention relates to a recombinant vector and a recombinant strain for expressing helicobacter pylori NapA protein, and a preparation method and application thereof, belonging to the technical field of biology. When the recombinant plasmid pNZ8110 delta sp-napA is constructed, a secretion signal sequence in pNZ8110 is removed, so that the NapA molecule expressed in the invention does not carry a secretion signal peptide and has a molecular weight of 15KD, and adverse effects on NapA bioactivity caused by the fact that the signal peptide cannot be cut in thalli when a recombinant strain fails to secrete and express protein are avoided. The lactococcus lactis recombinant strain for expressing the helicobacter pylori NapA can be used for manufacturing immune regulation medicines and producing health-care food with immune regulation efficacy, has important significance for preventing and treating diseases such as food allergy, immune suppression, tumor and the like, and can generate considerable social and economic benefits. |
priorityDate | 2017-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 135.