http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108728457-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-22 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y204-01245 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1051 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 |
| filingDate | 2018-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108728457-B |
| titleOfInvention | Trehalose synthase gene optimization sequence and application thereof |
| abstract | The invention provides a trehalose synthase gene optimized sequence, which comprises a DNA sequence shown as SEQ ID No. 1. The amino acid expressed by the optimized sequence of the trehalose synthase gene comprises a sequence shown as SEQ ID No. 2. According to the trehalose synthase gene optimized sequence, on the basis of not changing the final amino acid sequence, the rare codon or low-frequency codon of escherichia coli in the trehalose synthase gene sequence from streptomyces griseus is reasonably optimized through codon optimization, the bottleneck of gene translation of heterologous genes in the escherichia coli is broken through, the gene translation efficiency is improved, high-yield soluble expression in the escherichia coli is realized, the problem of low heterologous expression efficiency of the escherichia coli is solved, and the production cost of the trehalose synthase is greatly reduced. The invention can improve the industrial output value of the trehalose synthetase and reduce the production cost. |
| priorityDate | 2018-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 334.