Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_157f6ea8a2b996328769d9b5e934655f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fcaa03b795cd8da869d58e8f28bf52e5 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y308-01001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-14 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-01 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 |
filingDate |
2017-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75e81e9325d7c360038be1ca3f4fa767 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5cb506269508cbd369ded0ea38bf45bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aeccc7472cbbed48233721fc3daf7839 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6febe047d905b10bc9115605a24e672 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e9c408ae168bdf812fa9e38d26ab25d |
publicationDate |
2018-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-108728390-A |
titleOfInvention |
A genetically engineered bacterium producing A82846B and its preparation method and application |
abstract |
The invention discloses a genetically engineered bacterium producing A82846B, that is, the endogenous halogenase gene chaA is integrated in the genome of the starting bacterium Amycolatopsis orientalis, or is homologous with the endogenous halogenase gene chaA Engineering bacteria with no less than 84% exogenous halogenase gene. The invention also discloses a preparation method of the above-mentioned genetically engineered bacteria, and a method for fermenting the above-mentioned genetically engineered bacteria and obtaining A82846B from the fermentation liquid. The genetically engineered bacterium of the present invention overexpresses the introduced halogenase gene and produces A82846B, and the yield (mg/L) of A82846B or the proportion of the target product in the total product is significantly improved, and the present invention improves production efficiency and reduces production costs At the same time, it also reduces environmental pollution. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112430608-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112430608-B |
priorityDate |
2017-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |