http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108727397-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D221-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-153 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-056 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-153 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-056 |
| filingDate | 2018-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108727397-B |
| titleOfInvention | Phenanthridine Derivatives |
| abstract | The present invention mainly relates to the technical field of chemical synthesis, in particular to phenanthridine derivatives, namely compounds of general formula I, Wherein R 1 , R 2 are 1 or 2 ‑OCH 2 O‑, ‑OCH 3 , H, and when R 1 is H, R 2 cannot be H, 1 ‑OCH 3 , when R 2 is H , R 1 cannot be H, 1-OCH 3 , the anti-tumor activity of the compound was determined by MTT method, and the DNA unwinding experiment mediated by topoisomerase I and II showed that the compound of the present invention showed excellent anti-tumor activity, and was suitable for Both topoisomerases I and II have certain inhibitory effects. |
| priorityDate | 2018-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 77.