http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108727326-B

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filingDate 2018-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108727326-B
titleOfInvention Fluorescent probe for identifying cysteine and glutathione and preparation method and application thereof
abstract The invention discloses a fluorescent probe for identifying cysteine and glutathione, which has the structure as the following chemical formula: the preparation method of the fluorescent probe for identifying cysteine and glutathione comprises the steps of reacting S1 by taking 3-carboxyl-4-chloro-7-diethylamino coumarin and 3-hydroxy-N- (2-ethylmorpholine) benzamide as raw materials to obtain an intermediate; and S2, reacting the intermediate with p-nitrophenol serving as a raw material to obtain the probe. The fluorescent probe can identify and distinguish cysteine and glutathione from various amino acids and some common substances, has a lysosome targeting function, can directionally detect cysteine and glutathione in lysosomes, has good selectivity and high sensitivity on cysteine and glutathione, and has good application prospect in detection and analysis of cysteine and glutathione in environments or biological samples.
priorityDate 2018-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 45.