http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108727305-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_45050744e0b65b272a5aec65f6062304 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-82 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-82 |
| filingDate | 2018-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fcd45bd4fcf21a4fcd49bdfa6766626f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e142b9320da228541e43abc4bdf565cc |
| publicationDate | 2018-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108727305-A |
| titleOfInvention | The preparation method of Pramipexole impurity |
| abstract | The invention belongs to technical field of medicine synthesis, are related to a kind of preparation method of Pramipexole impurity：By the 6s-2 of dosage, 6,6- tripropyl -2,6- diamino -4,5,6,7- tetrahydro benzothiazols are dispersed in the organic basic solvent of dosage, are then stirred to react at a certain temperature.After completion of the reaction, it filters, the purified water of dosage is then added into filtrate, solid, solid filtering, filter cake dosage water washing to neutrality are precipitated at this time, vacuum drying obtains (S)-N, N- dipropyl -2- (the third amino) -2,3,4,5,6,7- hexahydro benzothiazole -6- amino, and structural identification has been carried out to it；The object of the present invention is to provide (S)-N, N- dipropyl -2- (the third amino) -2,3,4,5,6, the preparation method of 7- hexahydro benzothiazole -6- amino, the compound can control pramipexole raw medicine or the purity of its preparation as the impurity reference substance of Pramipexole. |
| priorityDate | 2018-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.