http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108727279-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-52 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 |
| filingDate | 2018-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108727279-B |
| titleOfInvention | Macitentan related substance D, its preparation method and use |
| abstract | The invention discloses a compound D represented by the following formula D, its preparation method, its use as a macitentan impurity reference substance, and a high-performance liquid chromatography method for separating and determining the impurity D in the macitentan crude drug. The method of the invention has mild reaction conditions and simple post-treatment, and can prepare the impurity D with the required purity on a large scale, which can be used as an impurity reference substance for mass analysis of macitentan. |
| priorityDate | 2018-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.