http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108727255-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_49d82b44ab1f5dd60b490f50b9d47231 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-38 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2018-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5d55e5a8708b78b46bb32b2b67206fb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8c243a25bdda22d60a88bda621a711d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_571dff6400262a1b1a9d759df25e55c3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90cb47469ab69dd85ef1dcf256c3c859 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5663b6c9f4fc92d5eb4dcf84dd7fbbe |
| publicationDate | 2018-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108727255-A |
| titleOfInvention | A kind of phenoxy bridge connection double-core copper（II）Complex and its preparation and application |
| abstract | The present invention relates to a kind of phenoxy bridges to join double-core copper（II）Complex and its preparation and application.Described phenoxy bridge connection double-core copper (II) complex has efficient antitumor action, and can be used as DNA cutting reagents and applied.The chemical formula of described phenoxy bridge connection double-core copper (II) complex is [Cu 2 (BHPMP)] Cl, wherein [Cu 2 (BHPMP)] + With specific structure formula.The preparation method of the complex is to make CuCl 2 With the H of specific structure 3 BHPMP carries out complex reaction in acetonitrile solvent, in 40~60 DEG C, and [Cu is obtained after purification 2 (BHPMP)] Cl solids.Present invention firstly discovers that phenoxy bridge connection copper (II) complex has stronger inhibiting effect to human cervical carcinoma cell (HeLa), non-small cell type lung carcinoma cell (A-549) and human breast cancer cell (MCF-7), significant antitumor activity is shown. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113024449-A |
| priorityDate | 2018-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.