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filingDate 2018-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_47aeb4ac0a47d5f77dba07ebfc0de6d8
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publicationDate 2018-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108721691-A
titleOfInvention A kind of modified porous chitosan gel rubber matrix carries medicine medical sponge and preparation method thereof
abstract The invention discloses a kind of modified porous chitosan gel rubber matrix to carry medicine medical sponge, the sponge is by chitosan multi-porous gel-type vehicle after the processing of microorganism modifier modification, and the polar group of the modified chitosan multi-porous gel matrix surface of recycling is completed the loading of pharmaceutical carrier and is made;The microorganism modifying agent includes falciform CELLULOLYTIC BACTERIUM, acetobacter xylinum and lactic acid bacteria;The pharmaceutical carrier is not reacted with chitosan multi-porous gel-type vehicle and be hydrophilic drug.The present invention generates a large amount of hydrophilic radicals by microorganism modifying agent biochemical reaction, then by the modification liquid spray containing high concentration hydrophilic radical after chitosan multi-porous gel surface completes modification;By pharmaceutical carrier liquid spray in modification of chitosan porous gel stromal surface, drug is completed by bonding action and is loaded, load pharmaceutical quantities of the matrix to hydrophilic medicament are increased;So that the medical sponge finally prepared is carried, pharmaceutical quantities are big, and medication effect is notable, lasting medicine.
priorityDate 2018-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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