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filingDate 2018-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108721247-B
titleOfInvention Preparation process of ropivacaine mesoporous bioactive glass composite microspheres
abstract The invention relates to a preparation process of ropivacaine mesoporous bioactive glass composite microspheres, which comprises the following steps: step 1: SiO 2 2 Preparing a colloidal crystal template; step 2: preparing an inverse colloidal crystal carbon template; and step 3: preparing MBGs; and 4, step 4: loading of drugs in MBGs; and 5: preparing composite microspheres; in step 5, firstly, uniformly dispersing MBGs and medicine-carrying-MBGs powder, flatly paving the powder on a flat, smooth and high-surface-strength plane, pressing the other flat, smooth and high-hardness surface on the MBGs and the medicine-carrying-MBGs powder for pressurization, adjusting the pressurization pressure, then dropwise adding a chloroform solution of PEG and PLA-PEG around the MBGs and the medicine-carrying-MBGs powder, wetting, and keeping ventilation at normal temperature until the chloroform is completely volatilized.
priorityDate 2017-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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