http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108715845-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2207-35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0331 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0275 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-01 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 |
| filingDate | 2018-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108715845-B |
| titleOfInvention | Construction method of esophagus epithelial tissue pol beta specificity knockout mouse esophagus precancerous lesion model |
| abstract | The invention specifically relates to a construction method of a mouse precancerous lesion model by specifically knocking out esophageal epithelial tissue DNA polymerase beta, 1) B6.pol beta flox/flox The mouse is mixed with ED-L2-Cre +/‑ The mouse is subjected to multi-generation hybridization, and the pol beta knockout mouse is obtained by identifying and screening the genotype of the mouse, wherein the genotype of the pol beta knockout mouse is B6.pol beta flox/flox .ED‑L2‑Cre +/‑ (ii) a 2) Inducing pol beta knockout mice by using a chemical carcinogen to form a pol beta knockout mouse esophageal epithelial tissue specific canceration model. The method is used for successfully constructing a mouse esophageal precancerous lesion model. |
| priorityDate | 2018-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.