http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108707604-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-10 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-907 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
filingDate | 2018-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108707604-B |
titleOfInvention | CNE10 gene knockout is carried out using CRISPR-Cas system in epidermal stem cells |
abstract | CNE10 gene editing is carried out for epidermal stem cells using CRISPR-cas system the present invention provides a kind of, more particularly to a kind of foundation of epidermal stem cells cell line for constructing CNE10 gene knockout.Two special gRNA are wherein constructed and obtained, the gene editing efficiency that CRISPR/Cas9 in epidermal stem cells is directed to CNE10 can be significantly improved.Epidermal stem cells CNE10 provided by the invention, which knocks out plasmid, has preferable genetic stability and higher target practice efficiency. |
priorityDate | 2018-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 427.