http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108707158-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-46 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-46 |
| filingDate | 2018-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108707158-B |
| titleOfInvention | Method for purifying cefpirome sulfate |
| abstract | The invention provides a method for purifying cefpirome sulfate, which comprises the following steps: (a) dissolving unqualified cefpirome sulfate sodium carbonate mixed powder in water, and adjusting the pH =3.8-5.5 by using a sulfuric acid aqueous solution after the solution is clear; (b) adding an organic solvent into the solution obtained in the step (a), reducing the temperature to 0-5 ℃, stirring to remove salt, and filtering; (c) adding active carbon into the filtrate obtained in the step (b) for primary decolorization, and filtering after the decolorization; (d) adjusting the pH =0.5-1.0 of the filtrate obtained in the step (c) by using a sulfuric acid aqueous solution, then adding activated carbon for carrying out secondary decolorization, and filtering after the decolorization; (e) and (4) crystallizing. The invention has simple operation, easy control and low cost. Through a special desalting process and a special decoloring process, the sodium sulfate removing capacity is strong, and an adsorption column is not needed. The cefpirome sulfate obtained by purification of the invention has the advantages of good stability, low color grade index and high content. |
| priorityDate | 2018-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.