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filingDate 2018-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108704137-B
titleOfInvention Opioid receptor partial agonist-loaded sustained release microspheres, and preparation method and application thereof
abstract An opioid receptor partial agonist-loaded sustained release microsphere, a preparation method and application thereof. The drug embedding rate of the sustained-release microsphere carrying the opioid receptor partial agonist is higher than 80%, the burst release of the drug is lower than 20% within 0.5h, and the sustained-release microsphere can be released at a constant speed for 1-15 days. The preparation method disclosed by the invention is simple in process, the obtained product is uniform in particle size, good in repeatability of each batch of product, easy for industrial production, and stable in curative effect of the medicine, the prepared microspheres are good in resuspension in water, and the industrial production cost is saved.
priorityDate 2018-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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