abstract |
The present invention relates to pharmaceutical agents useful for therapy and/or prophylaxis in mammals, and in particular to inhibitors of NF- κ B-induced kinase (NIK-also known as MAP3K14) useful for the treatment of diseases such as cancer, inflammatory disorders, metabolic disorders and autoimmune diseases. The invention is also directed to pharmaceutical compositions comprising such compounds; and to the use of such compounds or pharmaceutical compositions for the prevention or treatment of diseases such as cancer, inflammatory disorders, including obesity and diabetesMetabolic disorders, and autoimmune diseases. |