| abstract |
The present invention is described as cell cycle protein dependent kinase (CDK) inhibitors 4-amino-2- pyrimidinecarboxylic acids derivative, it is prepared and purposes.Specifically, the present invention provides general structures(Ⅰ)Compound represented, the analog derivative and its pharmaceutically acceptable salt, solvate, prodrug and medical composition are suitable for treatment and cell cycle protein dependent kinase(Especially CDK4/6)The related disease of activity and illness. |