http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108685903-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-366 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-366 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 |
| filingDate | 2018-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108685903-B |
| titleOfInvention | Application of the carnosol in preparation prevention and treatment experimental autoimmune encephalomyelitis drug |
| abstract | The invention discloses application of the carnosol in preparation prevention and treatment experimental autoimmune encephalomyelitis drug, with whole animal model experiment, the generation and development of experimental autoimmune encephalomyelitis can not only effectively be delayed by demonstrating carnosol, significantly reduce infiltration from peripheral inflammation cell to central nervous system, mitigate demyelinate degree, moreover it is possible to promote infiltration macrophage and M2 phenotype from the proinflammatory phenotype of intrinsic microglia to immunoloregulation function transformation.In addition, carnosol can inhibit Th17 cell differentiation and STAT3 phosphorylation, and block transcription factor NF-KB core transposition.Therefore, the drug that carnosol is used to prepare prevention and treatment autoimmune disease such as multiple sclerosis has huge potentiality. |
| priorityDate | 2018-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 141.