http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108676176-A

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filingDate 2018-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2018-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108676176-A
titleOfInvention A kind of preparation method of kadsura longepedunculata lignin ingredient
abstract The invention discloses a kind of preparation methods of kadsura longepedunculata lignin ingredient, and steps are as follows:Kadsura longepedunculata is extracted 13 times with 65 75% ethyl alcohol cold soaking of volume fraction, 3 5d, merges extracting solution every time, and extracting solution is concentrated under reduced pressure to give medicinal extract;Gained medicinal extract is diluted with water, uses petroleum ether, ethyl acetate and water saturated extracting n-butyl alcohol successively, is concentrated under reduced pressure, obtains acetic acid ethyl ester extract;By acetic acid ethyl ester extract large pore resin absorption column chromatographic isolation, first 7 column volumes are rinsed with 10% ethyl alcohol and remove big polar components, then use 75% ethanol elution, 10 column volumes, 75% eluent is collected, then detach through silica gel column chromatography, successively with volume ratio 46:1、23:1、17:1、5:1 chloroform methanol elution, collects 17:1 elution fraction, concentrates to obtain the final product.Preparation method is simple for this, and obtained lignin ingredient has significant antitumor, antiviral activity, can be used for drug preparation.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113912619-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115707482-A
priorityDate 2018-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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