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filingDate 2018-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108671127-B
titleOfInvention Onion extract and preparation method and application thereof
abstract The invention belongs to the field of medicine and pharmacology, and particularly relates to a onion extract and a preparation method and application thereof. The preparation method of the onion extract comprises the following steps: s1 taking sun-dried onion, crushing to obtain onion powder, placing the onion powder in a 2000mL triangular flask, adding an ethanol water solution, fully stirring, performing ultrasonic treatment, filtering, collecting an ethanol solution, and keeping residues for later use; s2, carrying out second and third extraction on the residue obtained in the step S1, wherein the extraction steps are the same as those in the step S1, combining the obtained alcohol solution with the alcohol solution obtained in the step S1, and recovering ethanol under reduced pressure until no alcohol smell exists, so that the obtained extract is the onion extract. The onion extract provided by the invention can obviously inhibit apoptosis of HT22 cells after OGD (OGD damage), can obviously reduce the cerebral infarction volume of newborn mice after hypoxic ischemic brain injury, and has a brain protection effect.
priorityDate 2018-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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