abstract |
The invention relates to an erythromycin ethylsuccinate gel and a preparation method thereof. The gel powder X-ray diffraction pattern has characteristic peaks at diffraction angles 2 theta of 4.4 +/-0.1, 5.1 +/-0.1, 6.3 +/-0.1, 9.1 +/-0.1, 9.3 +/-0.1, 10.1 +/-0.1, 11.3 +/-0.1, 12.7 +/-0.1, 13.3 +/-0.1, 13.9 +/-0.1, 15.5 +/-0.1, 16.1 +/-0.1, 17.9 +/-0.1, 18.2 +/-0.1, 18.7 +/-0.1, 18.9 +/-0.1, 20.7 +/-0.1, 21.2 +/-0.1, 21.9 +/-0.1, 23.0 +/-0.1 and 24.1 +/-0.1 degrees. The preparation method is simple, a gel matrix is not required to be used, and the safety is good; the content of erythromycin ethylsuccinate in the gel is high and is 9-50 wt%. |