http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108663346-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1458 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G2261-3223 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G2261-11 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G61-126 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G61-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 |
filingDate | 2018-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108663346-B |
titleOfInvention | L-cysteine fluorescent probe based on conjugated polymer/metal ion compound, and preparation method and application thereof |
abstract | Based on conjugated polymer/goldAn L-cysteine fluorescent probe belonging to an ion complex, a preparation method and application thereof. The fluorescent probe is a compound consisting of a conjugated polymer and metal ions, wherein the conjugated polymer is a polythiophene derivative (PT) with a side chain containing double carboxylate, and the structural formula is as follows: PT emits strong fluorescence in aqueous solution, with metal ions (M) n+ ) Upon binding, a complex is formed, and the fluorescence of the PT solution is quenched due to the paramagnetism of the metal ion. When L-cysteine (Cys) is added, Cys can react with M n+ To form a more stable complex Cys-M n+ Thereby enabling PT to be driven from PT/M n+ Released from the complex, and its fluorescence is restored. The PT/M n+ The compound fluorescent probe has the advantages of simple synthesis method, good water solubility, high response speed and high selectivity, can be used for quantitative detection of Cys in an aqueous solution, and can also be used for labeling and fluorescence imaging of Cys in living cells. |
priorityDate | 2018-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 80.