http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108658952-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12 |
| filingDate | 2017-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108658952-B |
| titleOfInvention | Preparation method of vilazodone hydrochloride IV crystal |
| abstract | The invention relates to the field of pharmaceutical chemistry, and provides a novel preparation method of vilazodone IV-type crystals. A method for preparing vilazodone hydrochloride IV type crystals is characterized by adding a vilazodone crude product and sodium metabisulfite into a crystallization solvent, heating until the vilazodone crude product and the sodium metabisulfite are dissolved, adding isopropanol hydrochloride, stirring for 0-24 hours at the same temperature under heat preservation, slowly cooling to a certain temperature for crystallization for 0-24 hours, carrying out suction filtration, washing a filter cake by using an organic solvent, and drying to obtain vilazodone IV type crystals. Compared with the existing preparation method of vilazodone IV crystal, the preparation method has simpler operation and obtains the vilazodone IV crystal with high purity in high yield. |
| priorityDate | 2017-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.