abstract |
The invention discloses a kind of synthetic method of 3 nitro Isoxazole derivative, this method is in the alcoholic solution system containing copper acetate and salt compounded of iodine, and aryl aldehyde carries out heterocyclization with nitromethane, obtains 3 nitro Isoxazole derivatives;This method reaction condition is mild, and catalyst and raw material are cheap, and reaction yield is high, is conducive to industrialized production. |