http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108658725-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C17-263 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C17-263 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C25-18 |
| filingDate | 2017-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108658725-B |
| titleOfInvention | The synthetic method of 2-fluorobiphenyl |
| abstract | A method for synthesizing 2-fluorobiphenyl belongs to the technical field of halogenated biphenyls. The o-fluoroaniline and benzene are used as raw materials, and the o-fluoroaniline is diazotized and subjected to a coupling reaction with benzene to obtain 2-fluorobiphenyl. Add trifluoroacetic acid, anhydrous magnesium sulfate, catalyst and benzene to the reaction kettle, stir and cool to 4-15 ℃, add isoamyl nitrite, control the temperature to be 20-30 ℃, add o-fluoroaniline dropwise thereto, dropwise add The process controls the reaction temperature to be 30-45°C. After the addition of materials, the reaction is stirred at 25-32°C for 1-3h. After the reaction, the reaction mixture is subjected to suction filtration, washing, drying and vacuum distillation to obtain 2-fluorobiphenyl. The synthesis method of the invention is simple, and the synthesized 2-fluorobiphenyl has high yield and high purity. |
| priorityDate | 2017-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 48.