http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108645905-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-327 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-327 |
filingDate | 2018-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108645905-B |
titleOfInvention | A method of hydrogen peroxide is detected based on solid nano hole |
abstract | The present invention relates to a kind of methods based on solid nano hole detection hydrogen peroxide, by beating different nano-pores on 10-100nm ultra-thin silicon nitride film, with a variety of silanization treatments, realize nanoporous surface and inner wall differentiation modification, by silane coupled molecule by peroxidase conjugate in nano-pore inner wall, it constructs controllable, stable, unimolecule hydrogen peroxide sersor part in highly sensitive nano-pore, by the nano-pore ion current signal for parsing enzymatic reaction, the model mechanism and rule of single enzyme molecule enzymatic reaction Km and Kcat in nano-pore, with Real_time quantitative detection hydrogen peroxide.The present invention reaches nanomole or less by the controllable modification of differentiation modification and horseradish peroxidase unimolecule in nano-pore inside and outside nano-pore, the small molecule real-time sensing detection method of the specificity of foundation, precision. |
priorityDate | 2018-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 53.