http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108640914-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate | 2018-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108640914-B |
| titleOfInvention | Method for synthesizing isoindole [2,1-b ] isoquinoline-5, 7-diketone compound |
| abstract | The invention discloses a method for synthesizing isoindole [2,1- b ]A method for preparing isoquinoline-5, 7-diketone compounds, belonging to the technical field of organic synthesis. Technique of the inventionThe key point of the scheme is that NH-isoquinolinone compounds, organic solvent, catalyst, oxidant and alkali are added into a reaction tube in turn or NH-isoquinolinone compounds, organic solvent, catalyst and oxidant are added into the reaction tube in turn, vacuumizing and CO charging are carried out for three times, then the reaction is heated and stirred in an oil bath at 120 ℃, T L C is followed to monitor the completion of the reaction, and the isoindole [2,1- b ]Isoquinoline-5, 7-diketone compounds. The invention overcomes the defects of the prior synthetic method of the compounds such as high toxicity and explosiveness of reactants, poor reaction selectivity, long synthetic route and the like, and is a method for synthesizing isoindole [2,1- b ]The efficient method for synthesizing the isoquinoline-5, 7-diketone compound has the advantages of easy preparation of raw materials, simple reaction operation, wide applicability of substrates, high yield and the like. |
| priorityDate | 2018-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 59.