| abstract |
The invention provides a substituted pyrimidinetrione compound, a composition containing the compound and an application of the compound, and discloses a pyrimidinetrione compound shown in a formula (I), or a crystal form, a pharmaceutically acceptable salt, a prodrug, a stereoisomer, a hydrate or a solvate of the pyrimidinetrione compound. The pyrimidinetrione compound and the composition containing the compound can be used for regulating Hypoxia Inducible Factor (HIF) and/or endogenous Erythropoietin (EPO), and can be used for preparing a medicine for regulating and controlling human anemia. |