| abstract |
The invention discloses a kind of polyphenol oxidase (PPO) inhibitor, the inhibitor is that N substituted-phenyls replace hydrazides thiosemicarbazide compound；The preparation method of polyphenol oxidase (PPO) inhibitor is：1mmol is sequentially added in the single necked round bottom flask of 100mL and replaces different sulfuric acid hydrocyanic ester and 1mmol substitution hydrazides, is added the dissolving of 15mL absolute ethyl alcohols, is reacted about 2 6h at room temperature, after reaction, it is filtered, obtained solid is recrystallized with absolute ethyl alcohol, and 30 DEG C of vacuum drying obtain target compound.Compound prepared by the present invention has higher inhibitory activity to polyphenol oxidase (PPO), can have a extensive future as the effective ingredient of antioxidant. |