| abstract |
The invention discloses a kind of season influenza RSV epidemic meningitis pneumococcus combined vaccine based on recombinant vector albumen, the combined vaccine include：Polysaccharide, epidemic meningitis capsular polysaccharide, Hib b and Multivalent pneumococcal capsular polysaccharide；Albumen, RSV immunogenic proteins and epidemic meningitis modified support albumen；The combined vaccine that polysaccharide is formed by connecting with albumen through connector, wherein connector is magnetic Nano microsphere.The present invention is used using magnetic Nano microsphere as connector, and four kinds of immune compositions, which are connected collaboration, generates immune response, produces good immune effect, and preparation process is simple, has good promotional value. |