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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6458
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64
filingDate 2018-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108593612-B
titleOfInvention Method for fluorescence enhancement detection of sulfur dioxide derivative based on polydopamine quantum dots
abstract The invention relates to a polydopamine quantum dot-based fluorescence enhancement type detection method for sulfur dioxide derivatives, and belongs to the technical field of nano biosensing. The method comprises the following steps: polydopamine quantum dots (PDADs) emitting blue fluorescence were synthesized at room temperature using Dopamine (DA) as the sole precursor. The sulfur dioxide derivative is added into the buffer solution containing the PDADs, so that the fluorescence of the PDADs is enhanced, and the high-sensitivity and selective detection of the sulfur dioxide derivative is realized. In addition, the fluorescent nano-probe can also realize the detection of sulfur dioxide derivatives in a complex system (human serum and urine) and the fluorescence imaging of intracellular sulfur dioxide derivatives. The polydopamine quantum dot fluorescent probe has the characteristics of simple synthesis, low biotoxicity, high sensitivity, good chemical stability and biocompatibility for detecting sulfur dioxide derivatives.
priorityDate 2018-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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