http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108588210-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-085 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6837 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6837 |
filingDate | 2018-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108588210-B |
titleOfInvention | Liver injury biomarkers, methods and applications comprising biological small molecules and genes |
abstract | The invention discloses biological markers for early detection and early warning of drug-induced liver injury. The biological markers are biological small molecules or differential genes, and the biological small molecules include: ethylene acetylglycine, 2-methyl-3 valeronic acid, 3 ‑Indolebutyric acid, LPC (20:2) and LPC (22:6). The invention also discloses a method for early detection and early warning of drug-induced liver injury, which quantitatively detects the concentration of biological small molecules or differential genes in a sample. The invention also discloses the application of the biological marker in scientific research and preparation of a diagnostic kit or diagnostic equipment for drug-induced liver injury. The changes of the biomarkers of the present invention occur before drug-induced liver injury, and have an early warning function; are beneficial to reduce the morbidity and mortality of drug-induced liver injury, help to improve the current situation of drug-induced liver injury prevention and control in my country, and effectively alleviate the A double burden on the patient's body and the economy. |
priorityDate | 2018-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 336.