http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108588028-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4703 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 |
| filingDate | 2018-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108588028-B |
| titleOfInvention | CIC cell model of targeting CDKN2A and preparation method thereof |
| abstract | The invention discloses a cell-in-cell (CIC) cell model of a target CDKN2A and a preparation method thereof. The method for preparing the cell-in-cell related cell model provided by the invention is used for preparing the cell-in-cell related cell model by regulating the expression of the CDKN2A gene in the target cell. The induced cell-in-cell model can be prepared by inhibiting the expression of the CDKN2A gene in the target cell; the suppression cell-in-cell model can be prepared by over-expressing CDKN2A gene in target cells. The method for promoting the formation of the CIC structure by interfering the expression of the CDKN2A gene is utilized. Aiming at the tumor cells with complete CDKN2A expression, CIC mediated intracellular death is hopeful to be promoted by the method, and the purposes of killing the tumor cells and inhibiting the growth of the tumor are achieved. |
| priorityDate | 2018-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 58.