http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108588017-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2509-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-115 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-135 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0072 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0668 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-36 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0775 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 |
filingDate | 2018-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108588017-B |
titleOfInvention | Amplification method of umbilical cord mesenchymal stem cells and application of umbilical cord mesenchymal stem cells in arthritis |
abstract | The invention relates to an improvement of an umbilical cord mesenchymal stem cell separation culture technology and application thereof in arthritis, and provides a separation culture method of umbilical cord-derived mesenchymal stem cells and application thereof in arthritis, which comprises the following steps: 1) obtaining mesenchymal stem cells from human umbilical cord by adopting an enzyme digestion method; 2) culturing the mesenchymal stem cells by using a DMEM/F12 culture medium added with basic fibroblast growth factors and platelet-derived growth factors in combination with the platelet-rich plasma; 3) the improvement of hyaluronic acid, methacrylic anhydride is added into hyaluronic acid to form a 3D biological scaffold, and mesenchymal stem cells can be fixed at the bone joint injury part for fixed-point repair; 4) the cultured mesenchymal stem cells are injected to the bone joints of the volunteers together with PRP and modified hyaluronic acid to treat osteoarthritis. |
priorityDate | 2018-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 116.