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filingDate 2018-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2020-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108587543-B
titleOfInvention Medical plugging adhesive and preparation method thereof
abstract The invention relates to a medical plugging adhesive and a preparation method thereof, wherein the medical plugging adhesive is prepared by mixing an aldehyde polysaccharide solution A and an amino polymer solution B, the aldehyde content of the aldehyde polysaccharide is 4-10 mmol/g, and the aldehyde polysaccharide is prepared by oxidizing natural polysaccharide or derivatives thereof with ozone and then with low-concentration periodate. Firstly, oxidizing natural polysaccharide or derivatives thereof by ozone, and then further oxidizing by using low-concentration periodate; the method obviously reduces the consumption of periodate, shortens the oxidation time, and simultaneously improves the aldehyde group content of the aldehyde polysaccharide so as to improve the bonding property of the medical plugging adhesive.
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