http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108586613-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70596 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-622 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2803 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6872 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-66 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 |
filingDate | 2018-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108586613-B |
titleOfInvention | Human antibody targeting CD19 and its preparation and application |
abstract | The present invention relates to a human antibody targeting CD19, and the sequence information of the variable region of the heavy chain of the human antibody targeting CD19 is shown in SEQ1, SEQ2, SEQ3 and SEQ4 respectively; the human antibody targeting CD19 The sequence information of the variable region of the light chain is shown in SEQ5, SEQ6, SEQ7, SEQ8, and SEQ9, respectively. The CD19-targeting human antibody sequence screened by the present invention can effectively bind to the target protein CD19 and show different affinities. The human antibody can be used for various applications targeting CD19, including chimeric antigens Receptor technology, constructed as a monoclonal antibody to kill tumor cells with ADCC or CDC mechanism, or combined with other antibodies to construct a bispecific antibody. |
priorityDate | 2018-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.