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filingDate 2018-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2020-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108586506-B
titleOfInvention Fluoroboron fluorovinylcoumarin derivative and synthetic method and application thereof
abstract The invention provides a fluoroboric fluorovinylcoumarin derivative and a synthesis method and application thereof, wherein the derivative is (E)7- (diethylamino) -3- (2- (5,5-difluoro-10- (4-methoxy) -1,7,9, -trimethyl-5H-dipyrrole [1,3,2]Diazaborine-3-) vinyl-4- (phenylpiperidine-1-) -2 h-chromen-2-one. The synthesis method of the derivative comprises the following steps: 1) n is a radical of 2 Under protection, 4-methoxybenzaldehyde and 2, 4-dimethylpyrrole are condensed in dichloromethane, DDQ is added for oxidation, and triethylamine and boron trifluoride are added for complexation to obtain a solid; 2) and (3) carrying out catalytic reflux reaction on the solid and 7-diethylamino-4-chloro-3-aldehyde-coumarin, and carrying out post-treatment to obtain the derivative. The derivative can be used for ClO in solution ‑ The detection of (3) can also be used for preparing arthritis detection reagents and can also be used as fluorescent dyes. The invention also provides a method for detecting ClO ‑ Of ClO, the process being ‑ The method realizes ratio type detection, shows high selectivity, and has simple detection process and accurate detection result.
priorityDate 2018-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 56.