http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108586454-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a4b1eac93fa8426bfd541c9e14e11860 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
filingDate | 2018-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0a2d80cf8d796a5c71467cde7e36334 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b9021d9cd69b85f38b362a20c50dc0e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e16e9aa7cccbb2a6ff0e0e6e1c268d6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2bf03fb0102191a5c15685d99893ee25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a79069cf21c6deff111e6aed776f19e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_930e96aa660c196bf20db170bdcdcde1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d60c7299dd26967ce9a7ad2eaf6a94c |
publicationDate | 2018-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108586454-A |
titleOfInvention | Tetrahydropyridine simultaneously [4,3-d] pyridine derivatives and application thereof |
abstract | The present invention relates to tetrahydropyridines shown in general formula I simultaneously [4,3 d] pyrimidine derivatives and its optical isomer, pharmaceutically acceptable salt, solvate or prodrug, compound shown in their preparation method and general formula I is the pharmaceutical composition of active constituent, wherein substituent R 1 、R 3 , L, P there is the meaning that provides in the description.The invention further relates to compounds of formula I to have strong ATX and EGFR kinase inhibitory activities, and it further relates to such compound and its optical isomer, pharmaceutically acceptable salt is being prepared for treating and/or preventing due to the application in the drug of ATX and EGFR unconventionality expression diseases caused, especially the purposes in preparing treatment and/or preventing the drug of fibrosis and cancer. |
priorityDate | 2018-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 787.