| abstract |
The invention discloses a dibenzoazepine compound, a preparation method and application thereof. The structure of the dibenzoazepine compound is shown in general formula 1 or general formula 2, wherein, R 1 is selected from methyl, hydrogen, chlorine or bromine, R 2 is selected from methyl or hydrogen, R 3 is selected from Hydrogen, chlorine atom, bromine atom, substituted or unsubstituted phenyl, naphthalene or pyridine; the substitution is phenyl ortho or meta or para hydrogen independently by fluorine, chlorine, methyl, methoxy One or more substitutions in group, nitrile group or trifluoromethyl group. The dibenzoazepine compounds of the present invention have significant inhibitory activity on cancer cells, especially human breast cancer cells, human gastric cancer cells, human liver cancer cells, human cervical cancer cells, and human acute promyelocytic leukemia cells. active. |