| abstract |
A kind of taxol and diaza provided by the invention And carbazole compound drug combination compositions, including active constituent and pharmaceutically acceptable auxiliary material, it is characterised in that：Active constituent diaza shown in gemcitabine and Formulas I And carbazole compound or its pharmaceutically acceptable salt form, gemcitabine and diaza in the active constituent And the mass ratio of carbazole compound or its pharmaceutically acceptable salt is (2 8)：1.The pharmaceutical composition anticancer therapeutic is good, toxic side effect is low；Due to diaza And carbazole compound is to the sensibility of gemcitabine, the two drug combination produces synergistic effect, to reduce the Clinical practice dosage of capecitabine, reduces large dosage and uses toxic side effect caused by capecitabine, safety clinical treatment index is improved, there is preferable potential applicability in clinical practice. |