http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108578399-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-221 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-223 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-223 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-221 |
filingDate | 2018-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108578399-B |
titleOfInvention | Application of amino acid ester compound in preparation of anti-CVB 3 virus medicine |
abstract | The invention discloses an application of an amino acid ester compound in preparation of a medicine for resisting CVB3 virus, and belongs to the technical field of antiviral medicines. Through a large number of biological experiments, the invention discovers that amino acid ester compounds (glycine ethyl ester, L-leucine methyl ester, L-alanine tert-butyl ester, beta-alanine ethyl ester, D-leucine methyl ester, glycine tert-butyl ester, beta-alanine tert-butyl ester and L-leucine tert-butyl ester) can inhibit replication and proliferation of CVB3 virus in cells, can strongly inhibit cytopathic effect caused by CVB3 virus, and improve the survival rate of infected cells, and can be used for preparing anti-CVB 3 virus medicines or medicines for treating diseases caused by CVB3 virus infection. The invention finds the new pharmaceutical application of the amino acid ester compound and provides a new direction for developing the anti-CVB 3 virus medicaments. |
priorityDate | 2018-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.