| abstract |
The invention discloses a coumarin-pyridine compound L, a preparation method and an application in H + detection. The structural formula of compound L is: ethyl 6-(7-N,N-diethylaminocoumarin-3-yl)-2-picoline-3-carboxylate. The compound is obtained by condensing coumarin ethyl ketone with DMFDMA to obtain an enaminone intermediate. The intermediate is directly prepared by a one-pot reaction in series with ethyl acetoacetate without separation and purification. The compound L has a low pKa value, sensitive, fast and reversible response to H + , good selectivity, strong anti-interference, and is suitable for pH detection in strong acidic environments. It is widely used in environmental monitoring, ecological protection, disease diagnosis and industrial It has wide application prospects in production and sewage inspection. |