http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108558744-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a3d7e466c44c7b54e2a48e4bf62665ef |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-71 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-71 |
| filingDate | 2018-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_876656f47b858352f99dbee8cb97f72d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2545bcdb497b44981d11d1097839934 |
| publicationDate | 2018-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108558744-A |
| titleOfInvention | A kind of preparation method of 2-methoxy-4-trifluoromethyl-3-pyridinesulfonyl chloride |
| abstract | The invention provides a preparation method of 2-methoxy-4-trifluoromethyl-3-pyridinesulfonyl chloride, which belongs to the field of fine chemicals. The present invention adopts raw material 2-chloro-4-trifluoromethylpyridine as starting raw material, through methoxylation, obtains 2-methoxyl-4-trifluoromethyl-3-pyridine compound, and then in butyllithium React with sulfur powder under the action to prepare 2-methoxy-3-mercapto-4-trifluoromethyl-3-pyridine compound, and then chlorinate and oxidize to prepare the final product 2-methoxy-4-trifluoro Methyl-3-pyridinesulfonyl chloride compound. Using sulfur powder in the process of preparing compound III and avoiding the use of thioether compounds can eliminate the foul odor brought about in the production process and reduce environmental pollution. Hydrogen peroxide is used for oxidation, and thionyl chloride is used for chlorination, avoiding the use of chlorine gas, effectively reducing the danger in the preparation and synthesis process, and improving the safety production factor. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110734397-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110734397-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111592557-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110981793-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110981793-A |
| priorityDate | 2018-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.